Publishing WASM wheels to PyPI for use with Pyodide

Jul 10, 2026

Pyodide 314.0 now allows Python packages built for Pyodide to be published directly to PyPI, eliminating the previous need for maintainers to manually build and host over 300 packages. Package maintainers can now build and publish Pyodide wheels to PyPI in the same way as native wheels, as demonstrated by Simon Willison with the luau-wasm package.

Why it matters: This change reduces the maintenance burden on Pyodide maintainers and enables easier distribution of Python packages compiled to WebAssembly.

Full story at: Simon Willison's Weblog ↗